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Clan: Telomerase (CL00004)

Summary

Telomerase clan

The Telomerase clan contains the RNA families Telomerase-vert, Telomerase-cil and Sacc_telomerase. Homology between these families has been established in the published literature [1-3].

This clan contains 3 families and the total number of sequence regions in the clan is 310.

Literature references

  1. Podlevsky JD, Bley CJ, Omana RV, Qi X, Chen JJ, Nucleic Acids Res. 2008;36:D339-D343.: The telomerase database. 18073191
  2. Romero DP, Blackburn EH, Cell. 1991;67:343-53.: A conserved secondary structure for telomerase RNA. 1840508
  3. Chen JL, Blasco MA, Greider CW, Cell 2000;100:503-514.: Secondary structure of vertebrate telomerase RNA. 10721988

Members

This clan contains the following 3 member families:

Telomerase-vert Telomerase-cil Sacc_telomerase

External database links

Secondary structures

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

Alignments

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family Num. regions Alignment
Sacc_telomerase (RF01050) 84 (27.1%) View
Telomerase-cil (RF00025) 28 (9.0%) View
Telomerase-vert (RF00024) 198 (63.9%) View