SNORA2 clan

The SNORA2 clan contains the RNA families SNORA16, SNORA2, snopsi28S-3327, snR189, snR46 and S_pombe_snR46. Homology between these families has been established in the published literature [1]. Researchers at the human snoRNA database (snoRNABase) have established that the following human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: SNORA2 and snR189, SNORA16 and snR46 [2].

This clan contains 6 families and the total number of sequence regions in the clan is 1,626.

Literature references

1. Li SG, Zhou H, Luo YP, Zhang P, Qu LH;, J Biol Chem. 2005;280:16446-16455.: Identification and functional analysis of 20 Box H/ACA small nucleolar RNAs (snoRNAs) from Schizosaccharomyces pombe. 15716270
2. Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836

Members

This clan contains the following 6 member families:

SNORA16 SNORA2 snopsi28S-3327 snR189 snR46 S_pombe_snR46

External database links

External sites:

1: http://www-snorna.biotoul.fr/human_yeast/

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
S_pombe_snR46 (RF01441)	1 (0.1%)	View
snR46 (RF01253)	55 (3.4%)	View
snR189 (RF01250)	26 (1.6%)	View
snopsi28S-3327 (RF00544)	39 (2.4%)	View
SNORA2 (RF00410)	1,217 (74.8%)	View
SNORA16 (RF00190)	288 (17.7%)	View