Summary
SNORA52 clan
The SNORA52 clan contains the RNA families SNORA66, snoR98, SNORA52, SNORA18, snoR80, snR49, snR5 and S_pombe_snR5. Homology between these families has been established in the published literature [1]. Researchers at the human snoRNA database (snoRNABase) have established that the following human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: U66 and snR49, SNORA52 and snR5 [2]. Researchers at the plant snoRNA database have established that the following arabadopsis, human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: snoR80 and SnR5, snoR98 and SnR5 [3].
This clan contains 8 families and the total number of sequence regions in the clan is 1,114.
Literature references
- Li SG, Zhou H, Luo YP, Zhang P, Qu LH;, J Biol Chem. 2005;280:16446-16455.: Identification and functional analysis of 20 Box H/ACA small nucleolar RNAs (snoRNAs) from Schizosaccharomyces pombe. 15716270
- Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836
- Brown JW, Echeverria M, Qu LH, Lowe TM, Bachellerie JP, Huttenhofer A, Kastenmayer JP, Green PJ, Shaw P, Marshall DF, Nucleic Acids Res 2003;31:432-435.: Plant snoRNA database. 12520043
Members
This clan contains the following 8 member families:
SNORA66 snoR98 SNORA52 SNORA18 snoR80 snR49 snR5 S_pombe_snR5External database links
| External sites: | 1: http://www-snorna.biotoul.fr/human_yeast/ 2: http://bioinf.scri.sari.ac.uk/cgi-bin/plant_snorna/conservation |
Secondary structures
This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.
Alignments
The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.
| Rfam family | Num. regions | Alignment |
|---|---|---|
| S_pombe_snR5 (RF01435) | 2 (0.2%) | View |
| snR5 (RF01252) | 58 (5.2%) | View |
| snR49 (RF01239) | 49 (4.4%) | View |
| snoR80 (RF01224) | 248 (22.3%) | View |
| SNORA18 (RF00425) | 328 (29.4%) | View |
| SNORA52 (RF00419) | 114 (10.2%) | View |
| snoR98 (RF00307) | 88 (7.9%) | View |
| SNORA66 (RF00155) | 227 (20.4%) | View |
