SNORD31 clan

The SNORD31 clan contains the RNA families SNORD31, snoZ17, snR67 and snoR35. Researchers at the human snoRNA database (snoRNABase) have established that the following human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: SNORD31 and snR67 [1]. Researchers at the plant snoRNA database have established that the following arabadopsis, human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: snoR35 and U31&SnR67 [2]. The following bioinformatic methods were used to confirm the relationship between these families: HMMER3 [3].

This clan contains 4 families and the total number of sequence regions in the clan is 618.

Literature references

1. Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836
2. Brown JW, Echeverria M, Qu LH, Lowe TM, Bachellerie JP, Huttenhofer A, Kastenmayer JP, Green PJ, Shaw P, Marshall DF, Nucleic Acids Res 2003;31:432-435.: Plant snoRNA database. 12520043
3. Eddy SR, PLoS Comput Biol. 2008;4:e1000069.: A probabilistic model of local sequence alignment that simplifies statistical significance estimation. 18516236

Members

This clan contains the following 4 member families:

SNORD31 snoZ17 snR67 snoR35

External database links

External sites:

1: http://www-snorna.biotoul.fr/human_yeast/ 2: http://bioinf.scri.sari.ac.uk/cgi-bin/plant_snorna/conservation

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
snoR35 (RF01281)	199 (32.2%)	View
snR67 (RF01177)	64 (10.4%)	View
snoZ17 (RF00266)	133 (21.5%)	View
SNORD31 (RF00089)	222 (35.9%)	View