The wikipedia text that you see displayed on our web site is a download from Wikipedia. This means that the information we display is a copy of the information from the Wikipedia database. The button above ("Edit wikipedia entry") takes you to the edit page for the article directly within wikipedia. You should be aware you are not editing our local copy of this information. Any changes that you make to the Wikipedia article will not be displayed by our site until we next download the article from Wikipedia. We currently download new content on a nightly basis.

Before you edit for the first time

Wikipedia is a free, online encyclopedia. Although anyone can edit or contribute to an article, Wikipedia has some strong editing guidelines and policies, which promote the Wikipedia standard of style and etiquette. Your edits and contributions are more likely to be accepted (and remain) if they are in accordance with this policy.

You should take a few minutes to view the following pages:

• Five pillars
• Policies and quidelines
• Wikipedia help contents
• Wikipedia Tips
• Editing help

Things you should know

How your contribution will be recorded

Anyone can edit a Wikipedia entry. You can do this either as a new user or you can register with Wikipedia and log on. When you click on the "Edit Wikipedia entry" button, your browser will direct you to the edit page for this entry in Wikipedia. If you are a registered user and currently logged in, your changes will be recorded under your Wikipedia user name. However, if you are not a registered user or are not logged on, your changes will be logged under your computer’s IP address. This has two main implications. Firstly, as a registered Wikipedia user your edits are more likely seen as valuable contribution (although all edits are open to community scrutiny regardless). Secondly, if you edit under an IP address you may be sharing this IP address with other users. If your IP address has previously been blocked (due to being flagged as a source of 'vandalism') your edits will also be blocked. You can find more information on this and creating a user account at Wikipedia.

If you have problems editing a particular page, contact us at rfam-help@ebi.ac.uk and we will try to help.

Information we would like to see added

We would value contributions that are referenced directly to the primary literature. Information on structure and function will be especially valuable.

Adding references is made much easier by this tool.

For a good example of what is possible in wikipedia, look at the Hammerhead Ribozyme entry.

Does Rfam agree with the content of the Wikipedia entry ?

Rfam has chosen to create Wikipedia entries for all of our RNA families and to open them up to community annotation. While the original Wikipedia article that we import was (in most cases) generated from Rfam annotations, the Wikipedia article you see now may bear little resemblance to that original text. The Wikipedia community does monitor edits to try to ensure that (a) the quality of article annotation increases, and (b) vandalism is very quickly dealt with. However, we would like to emphasise that Rfam does not curate the Wikipedia entries and we cannot guarantee the accuracy of the information on the Wikipedia page.

Contact us

The community annotation is a new facility of the Rfam web site. If you have problems editing or experience problems with these pages please contact us.

If you are interested in contributing to a wide range of articles relating to RNA, see the Wikiproject RNA page.

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You can either download the motif alignment or view it directly in your browser window. More...

Formatting options

You can view or download motif alignments in several formats. Check either the "download" button, to save the formatted alignment, or "view", to see it in your browser window, and click "Generate".

Alignment format:	Stockholm Pfam FASTA (gapped) FASTA (UNgapped)
Download/view:	Download View

There are 12 PDB entires which have been used to build the motif model.

The table of results below may be sorted by clicking on the column titles, or restored to the original order here.

Original order	PDB ID	PDB chain ID	PDB Residues
2	2gya	0	2535 - 2588
2	1yhq	0	544 - 612
2	1j5a	A	873 - 928
2	1c2w	B	2676 - 2731
2	1giy	A	908 - 963
2	3cpw	0	543 - 611
2	1FFK	0	953 - 1011
2	1NKW	0	874 - 927
2	1J5E		362 - 389
2	1S1I	3	1418 - 1443
2	1S72		954 - 1010
2	2AW4	B	847 - 930

There are 38 Rfam families which match this motif.

This section shows the families which have been annotated with this motif. Users should be aware that the motifs are structural constructs and do not necessarily conform to taxonomic boundaries in the way that Rfam families do. More...

Original order	Family Accession	Family Description	Number of Hits	Fraction of Hits	Sum of Bits	Image
3	RF00010	Bacterial RNase P class A	49	0.107	668.9
3	RF00024	Vertebrate telomerase RNA	8	0.216	92.5
3	RF00073	mir-156 microRNA precursor	4	0.400	41.6
3	RF00090	Small nucleolar RNA SNORA74	5	0.208	65.1
3	RF00100	7SK RNA	5	0.111	60.7
3	RF00102	VA RNA	3	0.056	31.9
3	RF00177	Bacterial small subunit ribosomal RNA	32	0.323	422.7
3	RF00222	Bag-1 internal ribosome entry site (IRES)	2	0.133	32.2
3	RF00334	Small nucleolar RNA SNORA3/SNORA45 family	3	0.500	43.5
3	RF00604	Small nucleolar RNA SNORD88	7	0.200	78.4
3	RF01064	microRNA mir-253	2	0.667	23.0
3	RF01268	Small Cajal body-specific RNA 2	2	0.100	21.5
3	RF01497	ALIL pseudoknot	3	0.115	44.4
3	RF01675	Pseudomonas sRNA CrcZ	2	0.105	21.4
3	RF01755	rmf RNA	4	0.250	50.6
3	RF01855	Plant signal recognition particle RNA	8	0.127	121.4
3	RF01857	Archaeal signal recognition particle RNA	7	0.132	92.5
3	RF01945	microRNA mir-1388	2	0.167	24.2
3	RF01959	Archaeal small subunit ribosomal RNA	22	0.256	285.3
3	RF01960	Eukaryotic small subunit ribosomal RNA	15	0.165	194.2
3	RF01989	Selenocysteine insertion sequence 3	3	0.125	34.0
3	RF02041	HOXA transcript at the distal tip, conserved region 2	3	0.120	31.4
3	RF02353	Bradyrhizobiaceae sRNA BjrC68	4	0.333	47.2
3	RF02502	Rhizobiales sRNA Atu_C8	3	0.111	33.7
3	RF02514	5' ureB small RNA	2	0.154	20.5
3	RF02531	Nrf2 internal ribosome entry site (IRES)	2	0.100	22.3
3	RF02540	Archaeal large subunit ribosomal RNA	90	0.989	3182.1
3	RF02541	Bacterial large subunit ribosomal RNA	99	0.971	3303.8
3	RF02542	Microsporidia small subunit ribosomal RNA	6	0.130	71.9
3	RF02543	Eukaryotic large subunit ribosomal RNA	26	0.295	335.2
3	RF02746	antisense RNA of rseC mRNA	2	0.286	21.2
3	RF02830	Streptomyces RNA 1601	2	0.333	23.8
3	RF02928	Actinomyces-1 RNA	34	0.144	366.5
3	RF02999	ivy-DE RNA	65	0.262	722.2
3	RF03041	poplar-1 RNA	2	0.091	34.1
3	RF03063	Streptomyces-metK RNA	4	0.105	46.4
3	RF03079	MISL RNA	10	0.227	135.4
3	RF03094	LAGLIDADG-2 RNA	2	0.080	24.7